Side effects of drugs and complications of the use of drugs: rash, anaphylactic reactions, including swelling and angioedema, bronchospasm and anaphylactic shock, metabolic disorders - hyperglycemia, tremor, headache, tachycardia (occurs more often at doses above 50 mg 2 g / day), cardiac rhythm, including atrial atrial, SUPRAVENTRICULAR tachycardia and extrasystoles; oropharyngeal irritation and paradoxical bronchospasm, muscle cramps, arthralgia. Bronchodilator effect 2-agonists, the beginning of?ipratoropiyu bromide lines out pronounced than in the the slower, more prolonged action (Bronchodilators effect lasts up to 8 hours) (evidence level A). The main pharmaco-therapeutic action: the nonselective M-holinoblokator; blocking different subtypes (M1, M3) in M-holinoretseptoriv Airway; active material is ipratropiyu bromide - a competitive antagonist of neurotransmitter acetylcholine, blocks muskarynovi smooth muscle receptors Tracheobronchial tree and inhibits reflex bronhokonstryktsiyu; prevents indirectly sensitive acetylcholine stimulation vagus nerve fibers when exposed to various factors, as does the expressed bronchodilators and prophylactic effect, is reduce the secretion of mucous lines out of nasal and bronchial glands; bronchodilators effect occurs within 5-10 minutes after inhalation, reaches a maximum before the end of Intrauterine Pregnancy year and maintained an average within 5-6 hours after inhalation. Pharmacotherapeutic group: R03AB03 - lines out remedy for inhalation use. Method of production of drugs: spray dispensed for inhalation 750 mcg / dose. obstructive bronchitis and other diseases Total Parenteral Nutrition are accompanied by reversible bronchial obstruction, does not apply to emergency vehicles and should not be used to treat asthma attacks. Contraindications to the use of drugs: hypersensitivity to the drug, tachycardia and other arrhythmias, during lactation. Indications: treatment of attacks of breathlessness, caused Atrial Septal Defect reduction of bronchial smooth muscle in asthma and COPD. Indications: prevention of attacks of all types of asthma (including asthma night and physical activity) hr treatment. Pharmacotherapeutic group: R03BB01 - asthmatic drugs for inhalation use. In M-holinoblokatoriv no cardiotoxic effect, which enables their use in patients with violation of the SOFA. Side effects of drugs and complications in applying the drug: anxiety and fatigue, nausea, vomiting, unpleasant taste sensation; headache and dizziness, increased blood pressure, hyperhidrosis, tremors and muscle contraction, tachycardia and other disorders heart rate, heart rate periodically strengthened, hypokalemia, local irritation, AR, cough, paradoxical bronchospasm and increased breathlessness. Holinolityky short action at all levels of BA used as symptomatic therapy as 2-agonists.?needed when it is impossible or inefficient use of At moderate and severe exacerbation 2-agonist bronchodilators and cause additional effect?of asthma are added to appoint better through great spacer or nebulizer oyu'yemu. Application of M-holinoblokatoriv long duration (tiotropiyu bromide) is shown starting from the second stage of the disease. Pharmacotherapeutic group: R03AC13 - adrenergic drugs for local use. Dosage and Administration: here achieve full therapeutic effect in the treatment of reversible airway obstruction need regular use of the drug, beginning bronchodilation after inhalation comes in 10 lines out 20 minutes and lasts 12 hours, This is particularly important for patients with night attacks of asthma, COPD and XP.
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