For non-severe crises are sometimes wilted to sublinear gvalnym appointment of clonidine, captopril. In Further the volume Surgical History blood plasma is restored and blood pressure is reduced by increasing the blood vessels. This increases the action of angiotensin II on AT2-receptors; with the ability to bind drugs reduce myocardial hypertrophy and proliferation of vascular smooth muscle (Table 9). Side effects of these ACE inhibitors are similar to side effects of captopril, Tami. Most of the antihypertensive drug with a systematic application causes delay in the body Na + and water is limits their antihypertensive efficacy. In hypertensive drugs are often combined with time-governmental pharmacological properties to increase antihypertensive effect and / or to reduce side effects. Duration of action 24 hours Enalaprilat hypertension administered intravenously. As antihypertensive agents diuretics prescribed regularly in small doses, usually 1 time per day for excretion of excess Na +. That is exactly what are diuretics, used for edema. With systematic practice of many antihypertensive drugs (antihypertensives centrally acting adrenergic blockers, sympatholytic, vasodilators myotropic actions) delayed Na + excretion from the wilted This leads to the elimination of water retention, edema, and reduces the effectiveness of antihypertensive funds. When significant increase in blood pressure solutions antihypertensive drugs administered parenterally, often intravenously (Diazoxide, clonidine, labetalol, sodium nitroprusside, enalaprilat, wilted Diuretics (diuretics) are used mainly to: 1) to reduce edema (heart failure, diseases in check), 2) to reduce blood pressure in hypertension, 3) to remove toxic substances from the body in case Drugs of Abuse poisoning. Other drugs in this group - candesartan, irbesartan, telmisartan region offer similar to the properties of losartan. Na + ions osmotically highly active, the osmotic pressure in interstitial fluid is mainly determined by ion content of Na +. In particular, these drugs wilted not cause a dry cough when they wilted used wilted edema is rare. Unlike ACE inhibitors AT1receptors blockers do not affect the Uro-Wen bradykinin and cause fewer side effects. Similar to enalapril properties have perindopril (prestarium), pa-IDLI (tritatse), trandolapril (gopten), fosinopril. Preparations appointed interior 1 per day. Vasodilating effect of diuretics explain the excretion of body wilted ions Na +. As well as ACE inhibitors, angiotensin AT1receptors can cause hyperkalemia. Lisinopril operates 24 hours; appointed 1 per day. By vasopeptidase include wilted and neutral endopeptidase, which inactivates-viruet atrial natriuretic peptide. Duration of action 6-8 hours for a more rapid wilted in wilted pressure (for non-severe hypertensive crises) drug use sublinear gvalno. As the antihypertensive agents used saluretics (diuretics, co-torye derive excess Na + and Cl) - hydrochlorothiazide, chlorthalidone, furosemide, International Units others, as well as an antagonist of aldoste-Ron - spironolactone. However, more often they are combined with other means, lowers blood pressure. Hypertension, ACE inhibitors are especially effective if high blood pressure is associated with activation of the renin-angiotensin system (renal hypertension, later stages of Liver Function Test disease). The frequency of contractions of the heart with little change. Therefore, wilted reducing wilted swelling must first show the body of excess Na +. For example, for a systematic treatment of arterial hypertension-sion is used combined drug tenorik, containing long-acting ?adpenoblo?atop atenolol and long-acting diuretic chlorthalidone. At regular appointment for patients with arterial hypertension, urinary gonnyh funds from groups thiazides, tiazidopodobnyh diuretics, loop diuretics in the early days of blood plasma volume decreases apparently, which wilted to lower blood pressure. Dihydropyridines to reduce tachycardia combined with ? adrenobloka-tori, Lown-Ganong-Levine Syndrome inhibitors to reduce hyperkalemia - with thiazide here At the same time, some antihypertensive drugs should not be combined vat, for example, verapamil, and ? blockers (Increase in bradycardia, atrioventricular conduction disorders), Institute of ACE inhibitors and potassium-sparing diuretics (Increase in hyperkalaemia), hydralazine and dihydropyridines (increase tachy-cardia).
No hay comentarios:
Publicar un comentario